Your Inside Scoop on Jacksonville’s Hottest Strains

Here’s what Jacksonville shoppers are reaching for this summer: a mix of proven classics and buzzy newcomers that keep flying off local menus. National trendsetters like Blue Dream, Wedding Cake, Runtz, Gary Payton, Apple Fritter, and RS11 continue to dominate 2025 lists—useful context when scanning Northeast Florida shelves.

On the ground in Jacksonville, Blue Dream remains a staple thanks to its approachable, anytime uplift. It’s easy to find in vaporizer formats at multiple storefronts; for example, AYR’s Dunn Avenue location routinely lists a Blue Dream cart, while Curaleaf’s Jacksonville menus feature Blue Dream across their Select and house lines. If a balanced, daytime-friendly profile is the goal, Blue Dream is still the city’s reliable green light.

Wedding Cake continues to be a top pick for evening relaxation and full-flavor dessert profiles. Its sustained popularity statewide mirrors national demand, so it frequently appears in rotation at major Florida operators that serve Jacksonville. When in doubt, check current menus at Curaleaf, Trulieve, or Sunnyside and look for “Cake” crosses that echo the same creamy-gassy DNA.

Runtz and White Runtz keep winning over shoppers who like candy-forward terp profiles and hybrid euphoria. Local menus often show Runtz derivatives in cartridges and disposables; for instance, Curaleaf’s Jacksonville pages highlight White Runtz in its Elite X Liquid Diamonds line, a fast mover when deals hit. For flavor-first vapers, these SKUs tend to disappear quickly on promo days.

Permanent Marker has surged from connoisseur favorite to mainstream must-try, and Jacksonville is no exception. It pops up in cartridges and infused formats at larger chains, often flagged among “best sellers” during site-wide sales. If you’re scanning for something modern and terp-saturated with a creative spark, this cultivar is a smart add to cart.

Apple Fritter continues its sweet, doughy streak in North Florida, especially in vape form. Curaleaf’s Select line routinely carries Apple Fritter carts in Jacksonville, appealing to shoppers who want dessert notes without the couchlock. For a similar flavor lane with a different twist, watch for “Berry Fritter” or “Fritter” crosses on weekly menus.

Gary Payton remains a go-to for hybrid focus and social energy. It shows up regularly on “what’s hot” lists nationwide, and when it lands in Jacksonville—often through brands aligned with Cookies genetics—it tends to rotate quickly. If you miss it in whole flower, check the pre-roll and cart sections; those formats reappear more often between drops.

Shoppers who like modern exotics should also keep an eye on RS11 (Rainbow Sherbet #11) and The Soap. RS11 is consistently cited among 2025 best-sellers; The Soap appears on MÜV’s Jacksonville Beach menu and scratches that bright, clean terp itch in pre-rolls and flower. Both speak to the city’s growing appetite for candy-citrus hybrids with a bit of sparkle.

Verano and partnered brands have helped Glitter Bomb and Cherry On Top gain traction near the beaches, while MÜV’s Hendricks location lists a rotating cast of fruit-forward vapes (Pineapple Mimosa, Summer Melon, Fresh Berry) that mirror the flavor-first trend shaping 2025. If you shop weekly, you’ll notice these SKUs anchor promo calendars and loyalty boosts.

Finally, Trulieve continues to seed Florida with new and revived genetics under house and partner banners. Their 2025 strain features—like Dark Rainbow and Space Age Cake #16—show how “cake,” “rainbow,” and “mints” families remain hot with Jacksonville patients who want rich, gassy-sweet profiles and evening relief.


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